Doctors use HIV in gene therapy to fix 'bubble boy' disease

Combined Shape

Eight babies who were born without a working germ-fighting system had their disease corrected by a gene therapy that was made from one of the immune system’s worst enemies — HIV, the virus that causes AIDS.

The boys had severe combined immunodeficiency syndrome, caused by lack of a gene that helps the immune system form. Without it, babies are unable to fight off infections. It’s also known as “bubble boy disease” because of a famous case in which a boy lived in a protective bubble to shield him from germs.

The therapy uses a version of HIV that’s been altered so it cannot cause disease but can carry the needed gene into the boys’ blood cells.

Results were published Wednesday by the New England Journal of Medicine. The treatment was pioneered by a doctor at St. Jude Children’s Research Hospital in Memphis.

The Western Journal has not reviewed this Associated Press story prior to publication. Therefore, it may contain editorial bias or may in some other way not meet our normal editorial standards. It is provided to our readers as a service from The Western Journal.

Truth and Accuracy

Submit a Correction →






We are committed to truth and accuracy in all of our journalism. Read our editorial standards.

Tags:
The Associated Press is an independent, not-for-profit news cooperative headquartered in New York City. Their teams in over 100 countries tell the world’s stories, from breaking news to investigative reporting. They provide content and services to help engage audiences worldwide, working with companies of all types, from broadcasters to brands.
The Associated Press was the first private sector organization in the U.S. to operate on a national scale. Over the past 170 years, they have been first to inform the world of many of history's most important moments, from the assassination of Abraham Lincoln and the bombing of Pearl Harbor to the fall of the Shah of Iran and the death of Pope John Paul.

Today, they operate in 263 locations in more than 100 countries relaying breaking news, covering war and conflict and producing enterprise reports that tell the world's stories.
Location
New York City




Conversation